About me
Professor Callegari is an expert in the physical behavior of granular materials, particularly their interactions with liquids (such as wettability and dissolution) and with other particles (such as flowability and electrostatics). His research contributes to pharmaceutical product development by addressing formulation challenges and improving powder processability. A key focus of his work is the design of composite granular materials through scalable techniques like melt coating and impregnation, which enhance formulation robustness and product quality. He has also developed methodologies to predict failure modes in pharmaceutical manufacturing—especially in continuous direct compression—by linking material properties to process performance, thereby supporting quality control and reducing production risks.
He has led and co-led numerous research projects funded by federal agencies such as the FDA and NSF, as well as by nonprofit organizations like USP and NIPTE. His industry collaborations include pharmaceutical giants like Johnson & Johnson and notable non-pharma companies such as Duracell and L’Oréal. His contributions to the field are reflected in the publication of approximately 40 peer-reviewed journal articles.